Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study

Uday Younis, Hussein and Herda, R. Boher and Afifah, H. Hassan (2013) Tube versus Gel Cross Match Methods at the National Blood Centre in Malaysia: A Comparative Study. International journal of medical sciences, 46 (1). pp. 1123-1126. ISSN 2051-5731

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Abstract

The objective was to determine the prevalence of positive gel cross match in situation of conjoint negative tube cross match and antibody screening in pre-transfusion testing practices. Study design: Prospective analysis of 2,600 samples with negative gel antibody screening results was done by tube and gel cross-match techniques in the Transfusion Medicine Unit in National Blood Center / Kuala Lumpur. Results: Positive gel cross-match was detected in 12 out of 2,600 (0.5%) tested samples that have negative both antibody screening and tube cross-match testing results. Six (50%) out of the total positive gel cross-match showed strong agglutination reaction (4+ and 3+ agglutination reaction grade). Conclusion: The situation of reactive gel cross-match with conjoint negative gel antibody screening and conventional tube cross match could occur despite using screening cells that cover most of the clinically significant antigens.

Item Type: Article
Uncontrolled Keywords: Pre transfusion Testing, Gel Cross-Match, Tube Cross-Match, Antibody Screening, Malaysia
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Health Sciences
Depositing User: Syahmi Manaf
Date Deposited: 13 Sep 2022 05:42
Last Modified: 13 Sep 2022 05:42
URI: http://eprints.unisza.edu.my/id/eprint/4403

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