Uday Younis, Hussein and Ahmed Ghazi, Faisal and Atif, Amin Baig (2014) The Free Alpha-Hemoglobin: A Promising Biomarker for β-Thalassemia. Molecular Biomarkers & Diagnosis, 5 (5). pp. 1-7. ISSN 2155-9929
Text
FH02-FPB-15-02862.pdf Restricted to Registered users only Download (757kB) |
Abstract
The purpose is to review the current knowledge and methods of determination of the free alpha hemoglobin with emphasis on its potential implications in patients with beta-thalassemia (β-thal).The severity of β-thal correlates with the extent of imbalance between α- and non-α-globin chains and the amount of the free alpha hemoglobin (free α- Hb) pool in the erythrocytes. To date, there is a lack of biomarkers that convey diagnostic and prognostic values in β-thal. Our ongoing research is aimed to evaluate the potential prognostic and diagnostic implications of free α-Hb to improve the care of patients with β-thal. Our ongoing research is aimed to quantify the free α-Hb for its potential prognostic and diagnostic implications towards improving the care of patients with various β-thal types in the years to come.
Item Type: | Article |
---|---|
Uncontrolled Keywords: | Free alpha haemoglobin; Biomarker; Beta-thalassemia; Alpha globin gene; Alpha globin chain; Malaysia |
Subjects: | Q Science > QR Microbiology > QR180 Immunology |
Divisions: | Faculty of Health Sciences |
Depositing User: | Rafidah Saaid |
Date Deposited: | 17 Jan 2022 07:38 |
Last Modified: | 17 Jan 2022 07:38 |
URI: | http://eprints.unisza.edu.my/id/eprint/4756 |
Actions (login required)
View Item |