Tualang honey supplementation improves oxidative stress status among chronic smokers

Harmy, Mohamed Yusoff and Aniza, Abd Aziz and Wan Syaheedah, Wan Ghazali (2015) Tualang honey supplementation improves oxidative stress status among chronic smokers. Toxicological and Environmental Chemistry, 97 (8). pp. 1017-1024. ISSN 02772248

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Abstract

Free radicals induced by cigarette smoking have been linked to an increase in oxidative stress resulting in smoking-related cardiovascular diseases. However, the possible effect of honey that has antioxidant property in improving oxidative stress status among smokers has not yet been reported. Hence, this study was to determine the effects of 12-week Tualang honey supplementation on F2-isoprostanes, superoxide dismutase, glutathione peroxidase, catalase, and total antioxidant status among chronic smokers. A total of 32 non-smokers and 64 chronic smokers were recruited from Quit Smoking Clinic and Health Campus, Universiti Sains, Malaysia. Smokers were randomized into two groups (n = 32/group) namely smokers without supplementation and smokers with honey supplementation (20 g/day) for 12 weeks. Blood was obtained from non-smokers and smokers at pre-intervention and from smokers at post-intervention. During pre-intervention, the levels/activity of F2-isoprostanes, total antioxidant status, and catalase were significantly higher while superoxide dismutase and glutathione peroxidase were lower in smokers than non-smokers. During post-intervention, in supplemented smokers, there were significant decrease in F2-isoprostanes and increase in total antioxidant status, glutathione peroxidase and catalase levels/activities compared with pre-intervention. This study indicates that honey supplementation improves oxidative stress status suggesting a beneficial role of honey in reducing the risk of cardiovascular diseases.

Item Type: Article
Uncontrolled Keywords: cigarette smoking; oxidative stress; Tualang honey; antioxidant; smokers
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine
Depositing User: Syahmi Manaf
Date Deposited: 13 Sep 2022 05:42
Last Modified: 13 Sep 2022 05:42
URI: http://eprints.unisza.edu.my/id/eprint/6534

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